http://www.canpcu.org/ Articles from Canadian PKU and Allied Disorders Sun, 04 Oct 2026 00:00:00 +0000 en http://www.canpcu.org/index.cfm?fuseaction=Feature.showFeature&featureID=75 Sun, 04 Oct 2026 00:00:00 +0000 HCU - Homocystinuria/ L’homocystinurie http://www.canpcu.org/index.cfm?fuseaction=Feature.showFeature&featureID=75 Homocystinuria (HCU) includes more than classical CBS-deficiency HCU. Remethylation disorders are part of the broader family of homocystinurias and can appear very differently from one person to another. Updated clinical guidance highlights why checking total homocysteine can provide an important clue when these rare disorders are suspected. http://www.canpcu.org/index.cfm?fuseaction=Feature.showFeature&featureID=55 Thu, 10 Sep 2026 00:00:00 +0000 HCU - Homocystinuria/ L’homocystinurie http://www.canpcu.org/index.cfm?fuseaction=Feature.showFeature&featureID=55 Health Canada’s new Canadian Clinical Trial Search Portal makes it easier to find clinical trials authorized in Canada by condition, treatment, location, recruitment status and more. For people living with rare metabolic disorders and their families, it provides a simpler way to discover research opportunities taking place closer to home. http://www.canpcu.org/index.cfm?fuseaction=Feature.showFeature&featureID=56 Thu, 10 Sep 2026 00:00:00 +0000 HCU - Homocystinuria/ L’homocystinurie http://www.canpcu.org/index.cfm?fuseaction=Feature.showFeature&featureID=56 Pegtibatinase is an investigational enzyme replacement therapy being studied for classical homocystinuria caused by cystathionine beta synthase deficiency. The clinical development program includes the COMPOSE, HARMONY and ENSEMBLE studies, with HARMONY currently evaluating the therapy in a pivotal Phase 3 trial. http://www.canpcu.org/index.cfm?fuseaction=Feature.showFeature&featureID=63 Thu, 10 Sep 2026 00:00:00 +0000 HCU - Homocystinuria/ L’homocystinurie http://www.canpcu.org/index.cfm?fuseaction=Feature.showFeature&featureID=63 RareKids-CAN is inviting youth with rare diseases and caregivers to share how they search for and use medication-related information. The study aims to identify gaps in current resources and help shape clearer, more useful pharmacology education for rare-disease families across Canada. http://www.canpcu.org/index.cfm?fuseaction=Feature.showFeature&featureID=53 Fri, 28 Aug 2026 00:00:00 +0000 HCU - Homocystinuria/ L’homocystinurie http://www.canpcu.org/index.cfm?fuseaction=Feature.showFeature&featureID=53 A rare diagnosis is important information, but it is not the whole story. Use CanChild’s F-Words for Child Development to introduce your child’s strengths, relationships, interests and hopes to their school team. http://www.canpcu.org/index.cfm?fuseaction=Feature.showFeature&featureID=54 Fri, 28 Aug 2026 00:00:00 +0000 HCU - Homocystinuria/ L’homocystinurie http://www.canpcu.org/index.cfm?fuseaction=Feature.showFeature&featureID=54 Un diagnostic rare est une information importante, mais il ne raconte pas toute l'histoire. Utilisez les « Mes mots préférés » de CanChild pour présenter à l'équipe scolaire les forces, les relations, les intérêts et les aspirations de votre enfant. http://www.canpcu.org/index.cfm?fuseaction=Feature.showFeature&featureID=25 Thu, 15 Jan 2026 00:00:00 +0000 HCU - Homocystinuria/ L’homocystinurie http://www.canpcu.org/index.cfm?fuseaction=Feature.showFeature&featureID=25 This article is presented in English. The article comes from Tribune News Network, Doha. Cet article est presente en anglais. L'article provient de Tribune News Network, Doha. Researchers from Qatar University (QU) published a study examining a specific genetic mutation called T236N in the CBS (cystathionine beta-synthase) enzyme.